Introduction Mechanical ventilation can be monitored by analysing particles in exhaled air as measured by particle flow rate (PFR).This could be a potential method of detecting ventilator-induced lung injury (VILI) before changes in conventional parameters can be detected.The aim of this study was to investigate PFR during different ventilation mod
Single center clinical analysis of macrophage activation syndrome complicating juvenile rheumatic diseases
Abstract Background Macrophage activation syndrome (MAS), an example of secondary hemophagocytic lymphohistiocytosis, is a potentially fatal complication of rheumatic diseases.We aimed to study the clinical and laboratory characteristics, treatment schemes, and outcomes of different rheumatic disorders associated with MAS in children.Early warning
Insights from the evaluations of the NIH Centers for Accelerated Innovation and Research Evaluation and Commercialization Hubs programs
Abstract Background: The National Institutes of Health launched the NIH Centers for Accelerated Innovation and the Research Evaluation and Commercialization Hubs programs to develop approaches and Stereo strategies to promote academic entrepreneurship and translate research discoveries into products and tools to help patients.The two programs colle
Generation of An Induced Pluripotent Stem Cell Line from Human Liver Fibroblasts from A Patient with Combined Hepatocellular-Cholangiocarcinoma
Objective: Combined hepatocellular-cholangiocarcinoma (cHCC-CC) is a rare type of primary liver cancer with characteristics of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC).The pathogenesis of cHCCCC is poorly understood due to a shortage of suitable in vitro models.Due to scarce availability of human liver tissue, induced pluripo
Developing an action concept inventory
We report on progress towards the development of an Action Concept Inventory (ACI), a test that measures student understanding of action principles in introductory mechanics and optics.The ACI 5 Piece Outdoor Chat Set also covers key concepts of many-paths quantum mechanics, from which classical Water Bottle Cap action physics arises.We used a mult